Reproducibility of the World Health Organization 2008 criteria for myelodysplastic syndromes
نویسندگان
چکیده
منابع مشابه
Reproducibility of the World Health Organization 2008 criteria for myelodysplastic syndromes.
The reproducibility of the World Health Organization 2008 classification for myelodysplastic syndromes is uncertain and its assessment was the major aim of this study. The different peripheral blood and bone marrow variables required for an adequate morphological classification were blindly evaluated by four cytomorphologists in samples from 50 patients with myelodysplastic syndromes. The degre...
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The presence of ≥ 15% bone marrow (BM) ring sideroblasts (RS) and < 5% blasts is required for a diagnosis of refractory anemia with ring sideroblasts. We examined the phenotypic and prognostic relevance of this "15%" RS threshold in 200 patients with myelodysplastic syndromes (MDS) without excess blasts and with ≥ 1% RS. The impact of RS% was assessed both as a continuous and categorical variab...
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We would like to point out that in each hybridization we can detect the germline band(s) of expected size, either from the nontumor cells in the marrow sample or the nontranslocated allele, serving as an additional internal control. Importantly, alternative enzyme/probe hybridizations were performed in our study according to recombinant bands already demonstrated with the " original " combinati...
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ژورنال
عنوان ژورنال: Haematologica
سال: 2012
ISSN: 0390-6078,1592-8721
DOI: 10.3324/haematol.2012.071449